"Interestingly, several antihistamine drugs, including clemastine, astemizole, azelastine, brompheniramine, and ebastine, which have been approved for treating allergy symptoms without side effects for decades, have been found to prevent SARS-CoV-2 infection or replication via protein-protein interaction analysis or drug library profiling (30–35). Another study revealed that the use of azelastine was associated with a reduced incidence of SARS-CoV-2 infection based on an analysis of over 219,000 electronic health records"
https://journals.asm.org/doi/10.1128/mbio.01088-24?s=09
https://journals.asm.org/doi/10.1128/mbio.01088-24?s=09